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Androgens, aging and sarcopenia: interconnected mechanisms and clinical implications As above mentioned, sarcopenia is characterized by a slow and progressive decrease in muscle mass and function, leading to reduced mobility, physical disability, increased risk of falls and fractures and consequently to a loss of independence

Sodium, due to the high solubility of its salts in the aqueous environment of the digestive tract, is almost completely absorbed into the enterocytes via sodium/glucose linked cotransporter (SGLT1, SLC5A1) and most importantly the sodium-hydrogen exchanger 3 (NHE3) (Nwia et al., 2022)