The 17 -HSDs are key factors that catalyze the steroid biosynthesis and metabolism in vertebrates ( 17 -HSDs can promote the mutual conversion between the active (17-hydroxy) form and the inactive (17-keto) form of specific steroids in an NADPH-dependent manner and participate in sex hormone metabolism ( CYP450 ). Aromatase is CYP450(19) , the rate-limiting enzyme in estrogen biosynthesis, through interaction with NADPH-cytochrome P450 reductase (CPR) and catalyzes a three-step hydroxylation to convert androgens (androstenedione and testosterone) to estrogen (estrone and estradiol) ( 2 , better than soybean lecithin and egg yolk lecithin, thereby promoting ovarian development
First, since most of the compounds are novel, their complete characteristics are not yet known, creating a need to understand their toxicology
doi: 10.2169/internalmedicine.52.8333 24 FuxeKMarcellinoDGenedaniSAgnatiL
Wernicke-Korsakoff in alcoholics Vitamin B2 (Riboflavin) Function: Energy production Deficiency signs: Cracks at mouth corners, sore throat, skin lesions Vitamin B3 (Niacin) Function: Metabolism, DNA repair Deficiency signs: Pellagra dermatitis, diarrhea, dementia Vitamin B6 (Pyridoxine) Function: Amino acid metabolism, neurotransmitter synthesis Deficiency signs: Irritability, depression, confusion, anemia Vitamin B12 (Cobalamin) Function: Red blood cell formation, nerve function Deficiency signs: Megaloblastic anemia, neuropathy, memory problems Folate (B9) Function: DNA synthesis, red blood cell formation Deficiency signs: Megaloblastic anemia, neural tube defects in pregnancy Fat-soluble vitamin deficiencies are less common but may occur in fat malabsorption
