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Notably, the roles performed by these cells in the disruption of the BBB by LPS may be interpreted as a succession or amplification, implying that the effects on the structure and function of the BBB by LPS are largely or even entirely through the mechanisms detailed in the direct actions section

(2012) identified four subtypes of adenomyosis, defined as due to direct endometrial invasion (Subtype I), endometriotic invasion from the outer uterus (Subtype II), de novo metaplasia (Subtype III) and heterogeneous, advanced disease of mixed phenotype (Subtype IV)

This suggests that disturbances in zinc homeostasis could be linked to ecological imbalances in the gut, potentially contributing to the pathophysiology of CD