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The c-jun NH2-terminal kinases (JNKs) are recognized as critical regulators of apoptosis, initiated in reaction to cellular damage

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Open questions Research on the regulatory enzymes of lactylation modifications in the central nervous system is currently limited

They justified the idea that the introduction of a staple to peptides decreases the enthalpic stabilization through the lowering of the entropic penalty and enhances the overall binding affinity, although it increases the hydrophobicity of peptides to a certain extent