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For the pathogenesis of systemic low-grade inflammation, pro-inflammatory transformation of the endothelium (endotheliosis) acquires particular importance, facilitating atherosclerosis, hypertension, thrombophilia, and microangiopathies [872,873,874,875,876,877]

Genomic analysis revealed three distinct phenotypes of Glo-I: GLO 1-1, GLO 1-2, and GLO 2-2 representing homo- and heterozygous expression of und [63, 64]

Many of the reactions that take place in the peroxisome ultimately reduce molecular oxygen to H 2 O 2 , and subsequently to H 2 O

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