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Description

This work presents an example of interplay among BBB/neurovasculature, the microbiome and neuroinflammation

Thanacoody H, Nijhout H, Reed M, Thomas C

found that ROS depletion not only reduced ox-mtDNA production and the binding to NLRP3, but also prevented NLRP3 deubiquitinating, thereby suppressing NLRP3 inflammasome activation