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Psychiatric referrals or outpatient follow-ups initially decreased from 2014 to 2018 (APC:-4.38%, 95% CI:-7.18 to -2.27) but then increased significantly after 2018 (APC:5.13%, 95% CI:3.47-7.32), reaching the highest incidence of 5.84% in 2023

Additionally, the active compound emodin extracted from Rhubarb has been utilized in modern medical research for treating related conditions such as intestinal barrier dysfunction