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Deficiency can occur due to dietary limitations, digestive disorders, or certain medications that interfere with B12 absorption

This biomarker-driven framework is essential for future clinical trials and therapeutic development, allowing for the identification of patient subpopulations most likely to respond to targeted interventions, such as anti-inflammatory therapies, neuroplasticity modulators, or specific sound therapies

In recent years, as the prognostic stratification of early breast cancer has become more precise, it has become a clinical consensus to tailor the intensity and duration of endocrine therapy according to risk stratification

The key is acting on early symptoms like bleeding gums before the disease progresses to advanced stages