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1b and c)

Strikingly, the mechanism of m6A methylation also involves the usage of SAM, which is part of one-carbon metabolism

Under conditions of oral dysbiosis such as periodontitis, F.n can disseminate to distant sites, and its enrichment in the gut is a hallmark of a disrupted microbial state, rarely observed in healthy individuals ( FnFabM gene, thereby enhancing its survival and colonization efficiency in the intestine ( F.n to thrive in the lower gastrointestinal tract (Zhu et al., 2024)