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MMP9 activation-mediated release of inflammatory cytokines represents one of the key neuroinflammatory mechanisms in ASD and exacerbates blood-brain barrier disruption [42, 43]

Membrane -glutamyl transpeptidase activity of melanoma cells: effects on cellular H 2 O 2 production, cell surface protein thiol oxidation and NF-B activation status

Indeed, knocking out all three urocortins does not have any major effect on basal corticosterone levels (62) although female urocortin 2 knockout mice exhibit a more subtle dysregulation with elevated basal ACTH and corticosterone secretion which is modulated by their estrogen status (63)

Molecular determinants of D-serine-mediated gliotransmission: from release to function