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Institutional Review Board Statement The study was conducted according to the guidelines of the Declaration of Helsinki

Summary Keywords neurodegeneration, microbiome, neuroinflammation, protein aggregation, gut microbiota, gut metabolome, gut inflammation, Alzheimers and Parkinsons diseases Citation Padhi P, Worth C, Zenitsky G, Jin H, Sambamurti K, Anantharam V, Kanthasamy A and Kanthasamy AG (2022) Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders

As an example, a drug may not be covered if it is prescribed to treat erectile dysfunction

Butyrate as a promising therapeutic target in cancer: from pathogenesis to clinic (review)