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They were anesthetized with desflurane inhalation, and then, 2 mL of 3% acetic acid was slowly infused into the distal colon using a suitable catheter

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In a lipopolysaccharide-induced rat model, pharmacological inhibition of CCR1 suppresses M1 polarization, promotes M2 polarization, and improves pain thresholds, urinary symptoms as well as bladder inflammation