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Considering the important role of macrophages in iron metabolism regulation, macrophage was chosen as the source of EVs in the present study

Acetylation of histones at the promoters of genes encoding TGF- or collagen can increase their expression, thereby promoting fibroblast activation and ECM production (77)

What Happens When You Have a Glutathione Deficiency

Abbreviations PsO: Psoriasis IMQ: Imiquimod PUVA: Psoralen + Ultraviolet A HaCaT: Human adult low calcium high temperature (immortalized keratinocyte cell line) PASI: Psoriasis area and severity index NF-B: Nuclear Factor kappa-light-chain-enhancer of activated B cells JAK: Janus kinase STAT: Signal transducer and activator of transcription STAT3: Signal transducer and activator of transcription 3 IL: Interleukin TNF-: Tumor necrosis factor-alpha TNF: Tumor necrosis factor IFN-: Interferon-gamma EGCG: Epigallocatechin gallate ROS: Reactive oxygen species Nrf2: Nuclear factor erythroid 2related factor 2 UV: Ultraviolet BALB/c: Mouse strain EE: Entrapment efficiency NLC: Nanostructured lipid carrier SLN: Solid lipid nanoparticles PVA: Polyvinyl alcohol MS: Multiple sclerosis AA: Arachidonic acid SK: Skin MA: Methacrylic acid SA: Stearic acid References Morrone A, DellAnna ML, Cristaudo A, Wubayehu T, Godefay H, Barnabas GA, et al