Importantly, the first committed step of the pathway, catalyzed by glucose-6-phosphate dehydrogenase (G6PD), is inhibited by NADPH [57]
Given that circulating LH levels did not differ between the control and rhGH rats, the activation of androgen production might indicate that rhGH has a direct effect on LCs
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The off-period is not optional, it is part of the protocol that ensures long-term success
