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Correlations between participants clinical and glycaemic characteristics and performance on the vMWMT, including both the hidden platform phase (time to first move, time to platform and path length) and the probe phase (time spent in the correct quadrant), were evaluated with Pearson or Spearman correlation coefficients, depending upon the normality of variable distributions

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Hexosamine pathway Excess glucose not metabolized via glycolysis can enter the hexosamine pathway, which leads to increased production of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), which is used for O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins