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2f and Supplementary Fig

15, 60

2025-03-05 14:47 Cagrilintide - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - DFVNYSKVLGRLRVGRASNRIIGSTILTKLI Asp - Phe - Val - Asn - Tyr - Ser - Lys - Val - Leu - Gly - Arg - Leu - Arg - Val - Gly - Arg - Ala - Ser - Asn - Arg - Ile - Ile - Gly - Ser - Thr - Ile - Leu - Thr - Lys - Leu - Ile 3365.8 Da 10.5 pH Henderson - Hasselbalch pKa CAS 1415456 - 99 - 3 Cagrilintide 31 - - - - NMR X Cagrilintide CGC - CGC - C Cagrilintide GC - C GTPcGMPcGMP GPKGTALDCT Cagrilintide GC - C cGMP - PKG Cagrilintide Cagrilintide Cagrilintide GC - C Cagrilintide PBS 0.1% - 1% pH Cagrilintide - 20 - 80** 4 1 - 2 - 20 GC - C GuanylinUroguanylin Cagrilintide GC - C Cagrilintide GC - C GC - C GC - C ANPBNP Cagrilintide [1] Wanner C, Inzucchi S E, Lachin J M, et al