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5-Amino-1MQ selectively inhibits nicotinamide N-methyltransferase (NNMT), a methyltransferase enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide

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If a patient is high-risk or has psychiatric problems, the surgeon may include additional checks, such as permitting only clear fluids or even scanning down to visualize the stomach pre-operatively