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This method, known as side chain-to-side chain cyclization, allows for greater flexibility in designing the peptides structure and function

Ann Intern Med 166(3):191200 Rena G, Lang CC (2018) Repurposing metformin for cardiovascular disease

In this review, we summarize the current knowledge on cell mechanisms involved in ferroptosis, we discuss how these processes relate to AD, and we analyze which ferroptosis-related genes are differentially expressed in AD brain dependant on cell type, disease progression and gender