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Other poor predictors of outcome are old age, female sex, high AST

Hierarchical analysis of 80 nuclei (from 40 adult myocytes) and 80 nuclei (from 80 neonatal myocytes) from N = 4 isolations

doi: 10.1038/nchembio.1416 16 DollSConradM

An increase in DIO3 activity can also be observed in consumptive hypothyroidism syndrome (associated with tumours such as hepatic hemangioendotheliomas, gliomas, neuroblastomas, colon carcinomas, gastrointestinal stromal tumours, and fibrous tumours), gestational hypothyroidism and treatments with oestrogens