Studies show methylglyoxal (MG) activated caspase-3 is enhanced in the presence of L-Buthionine sulfoximine
Funding This work was supported by the National Natural Science Foundation of China (82370039, 82001702), Guangdong Basic and Applied Basic Research Foundation (2022A15150062, 2022A1515140075), Medical Research Foundation of Guangdong Province (B2023056), the Science Foundation of Dongguan Science and Technology Bureau (20231800940452, 20231800940112, 200211800905022), Science and Technology Special Envoy Project of Songshan Lake District of Dongguan City (20234404-01KCJ-G), Songshan Lake Medical and Engineering Integration Project (4SG22310P), The Two Universities Paired and Cooperated Research Team Project of Guangdong Medical University (4SG22261G), the Innovation Project for College Students (S202210571065, S202310571086)

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Unfortunately, this rarely ends well, especially not for weight loss