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P4HB overexpression accelerates PHGDH ubiquitination and degradation, reducing antiapoptotic protein Bcl2 stability and inducing apoptosis [47]

Longer amino acid chains cost more to produce because each additional amino acid adds synthesis steps, purification requirements, and potential failure points

Reduced levels of serum motilin and gastrin, together with lower pro-inflammatory cytokines and reduced tissue NF-B and COX-2 levels, and increased serum somatostatin, vasoactive intestinal peptide, and tissue SOD, NO, and MDA levels were associated with genistein- and daidzein-rich fermented soy (shuidouchi) in an experimental animal model (275)

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