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Pharmaceuticals 15 , 855 (2022)

Chronic inflammation: Sustained immune activation that erodes tissues

The more visceral fat you carry, the worse these feedback loops become, creating a cycle where the fat itself makes more fat loss harder to achieve

Additionally, radiation-induced damage is amplified by the generation of reactive oxygen species (ROS), chemically reactive entities capable of oxidizing proteins and lipids and inducing single-strand DNA breaks (indirect effects)