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Molecular perspectives on selective estrogen receptor modulators (SERMs): progress in understanding their tissue-specific agonist and antagonist actions

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Notably, randomized controlled trials have revealed that TCM interventions reduced mortality rates, shortened hospitalization duration, and mitigated postoperative complications in AP patients compared to conventional therapies (Qiong et al., 2005)

These two mechanisms operate through distinct receptor systems and intracellular signaling cascades, and preclinical evidence suggests that concurrent activation may produce a greater growth hormone response than either compound alone