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DNA methylation and machine learning: challenges and perspective toward enhanced clinical diagnostics

However, in addition to the activation of sGC and its downstream effectors such as protein kinase G, NO also mediates signaling by oxidative S-nitrosylation of cysteine residues to form S-nitrosothiol groups within target proteins ( As NOS becomes uncoupled, an accompanying shift from S-nitrosylation to tyrosine nitration occurs and is the direct product of the changing ratio between ambient NO and superoxide produced by the enzyme

Baumeister U, Funke R, Ebnet K, Vorschmitt H, Koch S, Vestweber D (2005) Association of Csk to VE-cadherin and inhibition of cell proliferation