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doi: 10.1016/j.freeradbiomed.2016.05.015 [DOI] [PMC free article] [PubMed] [Google Scholar] 16

In addition, patients should be more proactive when they are receiving cyclophosphamide than at other times and should not wait until they have a high fever to get medical assistance

In contrast, positional polar amine substitutions around the quinolinium core not only improved NNMT inhibition as noted previously, but also enabled favorable passive and active transport across membranes (Tables 4 and 5)