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Description

Studies in mouse models of NAFLD and obesity, diet-induced or not, support the results seen in human studies with repression of Agxt expression 10, 52

[1] [9] In accordance with human findings, animals exposed to bromantane for extended periods of time do not appear to develop tolerance or dependence

The cells initially mounted adaptive responses, upregulating enzymes involved in glutathione biosynthesis (RRM2, GSR, GCLM) and fatty acid degradation (ALDH1B1, ACADVL)