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Description

10.1161/STROKEAHA.110.595058 43

Afterward, 150 g of protein was reduced and alkylated with 10 mM tris(2-carboxyethyl)phosphine hydrochloride (TCEP) and 40 mM 2-chloroacetamide (CAA), respectively, for 30 min at room temperature

Its diverse bioactive profile enables precision modulation of specific pathwaysakin to signaling bias in drug designto optimize efficacy while minimizing off-target effects