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Valdivieso AG, Clauzure M, Marn MC, Taminelli GL, Massip Copiz MM, Snchez F, et al

Due to the rapid proliferation of GBM, the TME is suppressed by factors such as acidity and hypoxia, rendering immunotherapy ineffective [95, 96]

21 ClarkeG.HarveyA

Briefly, the gene encoding the OsDHAR sequence (residues 2203) was amplified by PCR using Ex Taq polymerase (TaKaRa Bio Inc., Shiga, Japan) with forward and reverse primers for a cDNA template (Table S1)