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Figure 7 Discussion STW3-VI ( Hypericum perforatum L.) has been extensively used for the treatment of depression and anxiety disorders for its antidepressant and stress-reducing pharmacological properties (Butterweck et al., Moreover, it was suggested that dysfunction of the glutamatergic system may be involved in the pathophysiology of depression (Skolnick et al., 1996), because depression was found to be associated with abnormal high accumulation of the neurotransmitter glutamate in the brain (Sun et al., 2010)

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