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In this section, we will mainly summarize the nanocarrier materials used for lymphatic system drug delivery from two aspects: disease diagnosis and treatment, and lymph node imaging recognition and clearance

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Side Effects and Safety Side effects Across preclinical studies and the small human trials published to date (~28 subjects across pilot studies), the reported adverse events stay limited: Mild injection-site irritation (rare) No systemic toxicity at therapeutic doses in published reports Oral administration: mild GI upset in sensitive individuals No immunosuppression, hormonal disruption, or metabolic side effects have been observed