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Huang SK, Lu CW, Lin TY, Wang SJ (2022) Neuroprotective role of the B vitamins in the modulation of the Central Glutamatergic Neurotransmission.CNS Neurol Disord Drug targets

We have shown for the first time that stable deletion of GSTP1 in A2780 ovarian tumour cells significantly and selectively increases sensitivity to cisplatin and carboplatin, drugs routinely used to treat ovarian cancer, a notoriously drug-resistant and clinically intractable disease

Discussion To our knowledge, this is the first study to demonstrate an increase in CNS GSH levels with a noninvasive GSH augmentation strategy

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Kwee T.C., Kwee R.M