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Some comparative evaluation of adverse events including hepatotoxicity, related to antithyroid drugs has been done previously.29,77,78 In these investigations, the authors tried to find a relationship between the age of patients and the development of hepatotoxicity induced by methimazole and/or PTU

Table 1 Summary of clinical translation

As a negative control, a fraction of cells was incubated under identical conditions in the presence of an ALDH inhibitor, diethylamino benzaldehyde (DEAB)

Currently, AD treatment strategies primarily involve pharmacological interventions and acupuncture, which can only modestly delay disease progression but neither cure nor reverse the condition (4, 5)