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Inflammatory factors and oxidative stress damage the intestinal mucosal barrier, leading to reduced expression and impaired function of tight junction proteins, as well as increased intestinal permeability

[DOI] [PubMed] [Google Scholar] 35.DHaens G, Lemmens L, Geboes K, Vandeputte L, Van Acker F, Mortelmans L, Peeters M, Vermeire S, Penninckx F, Nevens F, et al

The convergence of advanced gene editing technologies, precision metabolomics, single-cell multi-omics, and artificial intelligence-driven drug discovery holds particular promise for transforming our understanding of mitochondrial neurodegeneration into clinically meaningful therapeutic advances in the coming decade

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