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References Novo Nordisk presents phase 3 data for next-generation amylin cagrilintide, leading to advancement into dedicated clinical Programme, 16 September 2025, Novo Nordisk, DAscanio AM, Mullally JA, Frishman WH

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The combination of these two measures can reveal a link between cochlear neuropathy and central neural hyperactivity, providing characteristic evidence that cochlear synaptopathyseen as a reduction in wave-I amplitudeis followed by compensatory central gain, reflected in the relatively stable amplitude of wave V 11,45

Data-dependent MS/MS (MS2) analysis was conducted in top speed mode with a 1-second cycle time, where the most abundant multiple-charged ( 2+ - 5+ ) precursor ions were selected for activation in order of abundance and detected in linear ion trap at rapid scan rate