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For instance, in otherwise healthy mice, NAC supplementation reduced mitochondrial activity in brown adipose tissue and increased markers of oxidative stress within mitochondria ( While our preliminary study produced several compelling observations, it is important to acknowledge several limitations

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For instance, interventions that selectively inhibit the pro-inflammatory mTOR-HIF-1 pathway while enhancing anti-inflammatory signaling could be a promising avenue for treating neurodegenerative diseases such as AD and Parkinsons disease (Lawson et al., 1990