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This apparent dramatic increase in ASD prevalence by CDC surveillance studies [338] over the past five decades has provoked a heated debate in the academic and medical community

Altered neurometabolite levels, including glutathione (GSH) and gamma-aminobutyric acid (GABA), have been proposed as potential contributors to the biology underlying ASD

In addition to characterizing the pressure transducer molecules, it will also be important to determine how ocular cells ignore steady-state IOP, and how they respond to and compensate for transient IOP fluctuations triggered by blinking, coughing, eye rubbing, circadian periodicity, swelling, ocular trauma, and exercise (e.g., swimming goggles, yoga practice)

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