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One aspect of the invention pertains to small molecule quinoline derived cations of Formula I, wherein: R 1 is C 1-4 alkyl R 2 , R 3 , R 4 , and R 5 are independently selected from the group consisting of: H, C 1-4 alkyl, halogen-substituted C 1-4 alkyl, NR 9 R 10 , and CN R 6 is H or halogen R 7 is H, methyl, or NR 11 R 12 R 8 is H, C 1-4 alkyl, halogen-substituted C 1-4 alkyl R 9 , R 10 , R 11 , and R 12 are independently selected from H and C 1-4 alkyl

JAMA 310:2435 [DOI] [PubMed] [Google Scholar] Lamberti P et al (2005) Effects of levodopa and COMT inhibitors on plasma homocysteine in Parkinsons disease patients

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5-Amino-1MQ is a small-molecule compound supplied in a 10 mg format for laboratory and in-vitro research applications