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Cruz-Aguado R, Fernandez-Verdecia CI, Daz-Surez CM, Gonzalez-Monzon O, Antunez-Potashkina I, et al

doi: 10.9758/cpn.2018.16.4.422

When GSH stores are reduced due to APAP overdose, the detoxification capacity of the liver is exceeded and NAPQI accumulates, leading to hepatocytes necrosis ( 4 )