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Dermatol 25 (Suppl

4.2.1 Common natural medicines in pathological scar treatment 4.2.1.1 Centella asiatica and its derivatives Centella asiatica and its derivatives have long been a research hotspot in the treatment of pathological scars using natural medicines, with 17 articles related to them included in this study

While typical proteasomal substrates such as CDKN1A (p21), HIF-1, and MCL1 were turned over at short timecourses, the substrates we found as TRIP12/UBR5-co-regulated proteins, including OTUD5, were relatively long-lived proteins (Fig