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NET formation was assessed by quantifying areas of decondensed chromatin DNA labeled with 4,6-diamidino-2-phenylindole (DAPI) (Extended Data Fig

86 Other groups have created fiber-reinforced hydrogels, and achieved stiffness values greater than 400 kPa, 80,87 resulting in replacement scaffolds for defects that require greater mechanical support

This is because aging per se is the major risk factor for most pathological conditions that limit healthspan and promote chronic disorders affecting the elderly, including immuno-senescence, cardio-metabolic disorders, osteoporosis, sarcopenia, arthritis, cataracts, neurodegenerative diseases and most cancers (Franceschi et al., 2018)

Frequency: Once or twice daily