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Ndyomugyenyi, R., Kabatereine, N., Olsen, A

In mouse models, A11 treatment ameliorated neuroinflammation, preserved neuronal integrity, mitigated AD pathology, and improved cognitive performance (Ralvenius et al., 2023)

However, our approach is a significant advance on these earlier methods, for the following reasons: snap-freezing of samples followed by reaction with IAM-TPP/IAM enables us to trap and stablise all reactive sulfur species simultaneously through their nucleophilic reactions to generate stable products, rather than leaving labile moieties that may be modified during sample workup

10.1021/jm990635c 27 HayD