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Early-stage (stage I) SCLC may be treated with surgery to remove the affected lobe followed by chemotherapy, with a combination of chemotherapy and radiation, or chemotherapy alone (ACS 2014d)

Conclusion ROS are the natural consequence of aerobic metabolism and are important for basic cellular functions, including proliferation, inflammation, apoptosis, and gene expression

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Mfn2-mediated mitochondrial fusion promotes autophagy and suppresses ovarian cancer progression by reducing ROS through AMPK/mTOR/ERK signaling