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Description

Cagrilintide monotherapy produced 10.8% mean body weight reduction at 26 weeks in the REWIND Phase 2 trial, while survodutide achieved 12.9% reduction at the highest evaluated dose (4.8mg weekly) in Phase 2 studies

Most people notice the most significant changes after 4 to 8 weeks of consistent use

Proceedings of the Nutrition Society 74

By replacing the PSMA-targeting moiety with ligands specific to other tumor-associated antigens (e.g., HER2, EGFR, or folate receptor), similar nano-PROTACs could be developed for other cancers