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A 2018 study published in the Environmental Science and Pollution Research Institute has found that lead exposure in preschool-age children can negatively affect coagulation ( 21 )

J., Kim, J

Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance

However, disruption in folate metabolism may be the underlying cause of folic acid-responsive NTD, and elevated homocysteine may simply be coincidental