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It contains monomeric phenolic compounds (catechin, epicatechin, and taxifolin) and condensed flavonoids (procyanidins), with antioxidant and antiinflammatory activities capable of stimulating the synthesis of the enzyme-induced nitric oxide synthase and antityrosinase activity leading to the suppression of melanin biosynthesis

doi: 10.1038/mi.2013.75 206 RaoYLeYXiongJPeiYSunY

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Also, the integrity of the bloodbrain barrier, which controls movement of cells and molecules into and out of blood vessels in the brain, weakens, 2,14 and the phospholipid-rich myelin sheaths that protect neurons and facilitate signal transmission deteriorate