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doi: 10.9758/cpn.2012.10.2.94 124 ShiraiY.FujitaY.HashimotoR.OhiK.YamamoriH.YasudaY.et al

The Crumbs complex, including PALS1, LIN7c, and angiomotin (AMOT), interacts with TAZ/YAP and transmits cells by promoting TAZ/YAP phosphorylation

Purinergic Signal 13:305318

The full effects, particularly in aesthetic treatments, tend to become more visible and improve over several months as the body produces new collagen and skin cells