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Environmental exposure adds additional reactive species such as ozone and nitrogen dioxide [8]

Under certain nutrient deficient conditions, cancer cells undergo cell death whereas normal healthy cells survive because they are more metabolically flexible ( SLC7A11 mediated cystine uptake is crucial to main redox homeostasis and biomass incorporation in cells ( Figure 2 )

Sulfur is found in the two amino acids that are precursors to glutathione and contribute to its synthesismethionine and cysteinemaking this a critical mineral required for glutathione production