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8C and 8D show mitochondrial superoxide levels in 143B cells assessed by flow cytometry using MitoSOX

Interestingly, MRI studies have linked cognitive impairment in CP survivors to structural brain changes, including reduced gray and white matter volumes in limbic areas connected to the hypothalamus, as well as an association between impaired long-term memory and reduced gray matter volumes in the posterior cingulate cortex in adolescents with CO CP [157]

Figure 1 D-Lactate D-lactate exerts metabolically inert in mammals (62) because of the absence of specific cytosolic lactate dehydrogenase (D-LDH) to metabolize D-lactate into pyruvate (63, 64)

Fatemi SH, Aldinger KA, Ashwood P, Bauman ML, Blaha CD, Blatt GJ, et al