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The authors suggest that inhibition of FAO may lead to an overall decrease in cancer cell survival, while an increase in CPT1 activity, such as the PRL-mediated response, may provide a supportive environment for malignant cells 36

AMPK is a critical bioenergy sensor, and the functional role of AMPK has been extensively studied in lipid metabolism (fatty acids, mitochondria, and cholesterol), glucose metabolism, protein synthesis, inflammation mitigation, mitochondrial biogenesis, apoptosis, and many other aspects [21]