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Battula VL, Chen Y, Konopleva M, Andreeff M

To date, two ASC-based early-phase organoid clinical trials have been registered: the transplantation of autologous colon organoids as treatment of ulcerative colitis (clinical trial UMIN000030117, Japanese Registry) and the transplantation of salivary gland organoids for treatment of radiation-induced xerostomia (dry mouth syndrome) (clinical trial NCT04593589)

The cloned hybridoma cells were initially cultured in a RPMI1640 medium supplemented with 10% FBS, 1% non-essential amino acids, 0.5% penicillin-streptomycin and 1% Na-pyruvate, with the addition of Briclone (NICB) if needed

doi: 10.1016/j.tibtech.2007.02.005